Signs and Symptoms

Signs and symptoms of NF2 mainly depend on the location of a tumor or tumors growing against or on a nerve(s). Some symptoms may not involve a tumor, such as, Cafe Au Lait skin spots. The illustration below outlines the possible tumor types in which an individual with NF2 can possess. NF2 affects each individual differently and NOT ALL of the tumors, signs and symptoms, listed may occur.  This is only a reference list.

A figure of NF2 symptoms
An illustration of the many tumor types that can be found within a person with NF2. Please note, NOT ALL of the tumors listed will occur in a person with NF2; this is only a reference list.

Brain Tumors

  • Schwannomas on Cranial Nerves I – XII; most notably, Bilateral Vestibular Schwannomas of Cranial Nerve VIII
  • Meningiomas
  • Gliomas

Sign and Symptoms:

Spinal Cord Tumors

  • Schwannomas
  • Meningiomas
  • Ependymomas
  • Astrocytomas

Sign and Symptoms:

  • Drop Foot
  • Scoliosis
  • Tingling/Numbness of Limbs
  • Pain

Peripheral Nerve Tumors

  • Brachial Plexus Tumors (Upper Arm/Neck)
  • Sciatica Nerve Tumors (Lower Back/Hip/Upper Leg)
  • Peroneal & Tibia Nerve Tumors (Lower Leg)
  • Median Nerve Tumors (Arm)
  • Subcutaneous Schwannomas of the Dermis (skin)

Sign and Symptoms: